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[HSK]Good leaving group och poor leaving group i reaktioner
- Grutil
- Medlem
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- Registrerad: 2015-06-23
- Inlägg: 4
[HSK]Good leaving group och poor leaving group i reaktioner
Hej!
Jag har en del funderingar som jag skulle uppskatta om det förklarade förenklat. Läs nedan följande:
Substitution reactions do not occur with alcohols unless ̄OH is converted into a good leaving group.
Vad menas egentligen med good leaving group och poor leaving group?
Tack!
- sprite111
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Re: [HSK]Good leaving group och poor leaving group i reaktioner
Any time a new bond is formed, take a look at the atom that’s accepting the lone pair of electrons. Does it have a full shell of electrons? Oftentimes it does. If so, that means you’re going to have to break a bond that’s attached to that atom. If it’s a single bond you’re breaking, what you end up creating is called a leaving group.
So if the leaving group is positively charged, it will become neutral, and if it’s neutral, it will become negative.
The identity of the leaving group is crucial to whether the reaction will happen at all. There are “good” leaving groups and there are “bad” leaving groups. Reactions are more likely to take place when you can displace a good leaving group.
Svaret på din fråga finns nog nedan. Ovan var lite bakgrund till vad Leaving group är för något.
What makes a leaving group “good” or “bad”? Thankfully, there’s one simplifying factor to look at when deciding this: its basicity. Good leaving groups are weak bases.
How do we know what are weak bases? There’s a useful tool for that – it’s called a pKa table. Many pKa tables only specifically give you the identity of the acid, but if you think about it, it also gives you information about the conjugate base of each acid. The conjugate base is the part left over when you lose H+. The stronger the acid, the weaker the conjugate base.
And the weaker the conjugate base, the better the leaving group. So a pKa table is a great guide to leaving group ability
Citat från (20:07):
http://www.masterorganicchemistry.com/2 … ng-group/,
-Good leaving groups are weak bases. They’re happy and stable on their own.
Någon annan kanske har en enklare förklaring samt varför det är som det är
Senast redigerat av sprite111 (2017-01-25 13:20)
Anyone who considers arithmetical methods of producing random digits is, of course, in a state of sin.
//John von Neumann